Ufm1-specific protease 2 (UFSP2)
Homo sapiens — UniProt Q9NUQ7
Data last refreshed: (UniProt release unknown)
Key facts
Ufm1-specific protease 2 (UFSP2) is a protein from Homo sapiens identified by UniProt accession Q9NUQ7, 469 residues long. MolForge cross-references it against 0 known binders and 133 disease associations.
- UniProt accession: Q9NUQ7; gene symbol UFSP2.
- Organism: Homo sapiens.
- Length: 469 amino acids.
- Top disease associations (Open Targets): spondyloepimetaphyseal dysplasia, di rocco type, hip dysplasia, Beukes type and Intellectual disability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ufm1-specific protease 2 |
|---|---|
| UniProt accession | Q9NUQ7 |
| Gene | UFSP2 |
| Organism | Homo sapiens |
| Length | 469 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (133)
Diseases linked to this target (Open Targets).
- spondyloepimetaphyseal dysplasia, di rocco type · score 0.62
- hip dysplasia, Beukes type · score 0.62
- Intellectual disability · score 0.55
- developmental and epileptic encephalopathy 106 · score 0.54
- Seizure · score 0.49
- Global developmental delay · score 0.46
- Microcephaly · score 0.45
- Strabismus · score 0.37
- epilepsy · score 0.37
- Delayed speech and language development · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NUQ7-F1 | alphafold | PREDICTED | 91.18 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NUQ7.
Amino-acid sequence (469 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UFSP2?
The strongest Open Targets associations for UFSP2 are spondyloepimetaphyseal dysplasia, di rocco type, hip dysplasia, Beukes type, Intellectual disability, developmental and epileptic encephalopathy 106 and Seizure.
How long is the UFSP2 protein?
The Homo sapiens UFSP2 protein (UniProt Q9NUQ7) is 469 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NUQ7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NUQ7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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