ATP-binding cassette sub-family F member 3 (ABCF3)
Homo sapiens — UniProt Q9NUQ8
Data last refreshed: (UniProt release unknown)
Key facts
ATP-binding cassette sub-family F member 3 (ABCF3) is a protein from Homo sapiens identified by UniProt accession Q9NUQ8, 709 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q9NUQ8; gene symbol ABCF3.
- Organism: Homo sapiens.
- Length: 709 amino acids.
- Top disease associations (Open Targets): mathematical ability, mean corpuscular hemoglobin and brain measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ATP-binding cassette sub-family F member 3 |
|---|---|
| UniProt accession | Q9NUQ8 |
| Gene | ABCF3 |
| Organism | Homo sapiens |
| Length | 709 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- mathematical ability · score 0.20
- mean corpuscular hemoglobin · score 0.18
- brain measurement · score 0.12
- lean body mass · score 0.12
- Familial prostate cancer · score 0.11
- prostate cancer · score 0.11
- prostate carcinoma · score 0.11
- mean corpuscular volume · score 0.10
- neuroimaging measurement · score 0.09
- hypertension · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NUQ8-F1 | alphafold | PREDICTED | 81.42 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NUQ8.
Amino-acid sequence (709 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ABCF3?
The strongest Open Targets associations for ABCF3 are mathematical ability, mean corpuscular hemoglobin, brain measurement, lean body mass and Familial prostate cancer.
How long is the ABCF3 protein?
The Homo sapiens ABCF3 protein (UniProt Q9NUQ8) is 709 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NUQ8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NUQ8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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