GTPase IMAP family member 4 (GIMAP4)
Homo sapiens — UniProt Q9NUV9
Data last refreshed: (UniProt release unknown)
Key facts
GTPase IMAP family member 4 (GIMAP4) is a protein from Homo sapiens identified by UniProt accession Q9NUV9, 329 residues long. MolForge cross-references it against 0 known binders and 82 disease associations.
- UniProt accession: Q9NUV9; gene symbol GIMAP4.
- Organism: Homo sapiens.
- Length: 329 amino acids.
- Top disease associations (Open Targets): eosinophil count, lymphocyte count and triglyceride measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | GTPase IMAP family member 4 |
|---|---|
| UniProt accession | Q9NUV9 |
| Gene | GIMAP4 |
| Organism | Homo sapiens |
| Length | 329 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (82)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.33
- lymphocyte count · score 0.31
- triglyceride measurement · score 0.29
- reticulocyte count · score 0.28
- neutrophil percentage of leukocytes · score 0.28
- lymphocyte percentage of leukocytes · score 0.28
- C-reactive protein measurement · score 0.28
- high density lipoprotein cholesterol measurement · score 0.26
- von Willebrand factor measurement · score 0.25
- eosinophil percentage of leukocytes · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NUV9-F1 | alphafold | PREDICTED | 85.47 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NUV9.
Amino-acid sequence (329 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GIMAP4?
The strongest Open Targets associations for GIMAP4 are eosinophil count, lymphocyte count, triglyceride measurement, reticulocyte count and neutrophil percentage of leukocytes.
How long is the GIMAP4 protein?
The Homo sapiens GIMAP4 protein (UniProt Q9NUV9) is 329 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NUV9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NUV9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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