Acyl-coenzyme A oxidase-like protein (ACOXL)
Homo sapiens — UniProt Q9NUZ1
Data last refreshed: (UniProt release unknown)
Key facts
Acyl-coenzyme A oxidase-like protein (ACOXL) is a protein from Homo sapiens identified by UniProt accession Q9NUZ1, 547 residues long. MolForge cross-references it against 0 known binders and 141 disease associations.
- UniProt accession: Q9NUZ1; gene symbol ACOXL.
- Organism: Homo sapiens.
- Length: 547 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, lymphocyte count and erythrocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Acyl-coenzyme A oxidase-like protein |
|---|---|
| UniProt accession | Q9NUZ1 |
| Gene | ACOXL |
| Organism | Homo sapiens |
| Length | 547 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (141)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.50
- lymphocyte count · score 0.48
- erythrocyte count · score 0.47
- mean corpuscular hemoglobin · score 0.47
- mean corpuscular hemoglobin concentration · score 0.46
- mean reticulocyte volume · score 0.45
- neutrophil percentage of leukocytes · score 0.43
- chronic lymphocytic leukemia · score 0.41
- total blood protein measurement · score 0.40
- lymphocyte percentage of leukocytes · score 0.39
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NUZ1-F1 | alphafold | PREDICTED | 92.09 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NUZ1.
Amino-acid sequence (547 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ACOXL?
The strongest Open Targets associations for ACOXL are mean corpuscular volume, lymphocyte count, erythrocyte count, mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration.
How long is the ACOXL protein?
The Homo sapiens ACOXL protein (UniProt Q9NUZ1) is 547 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NUZ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NUZ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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