Integrator complex subunit 9 (INTS9)
Homo sapiens — UniProt Q9NV88
Data last refreshed: (UniProt release unknown)
Key facts
Integrator complex subunit 9 (INTS9) is a protein from Homo sapiens identified by UniProt accession Q9NV88, 658 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.
- UniProt accession: Q9NV88; gene symbol INTS9.
- Organism: Homo sapiens.
- Length: 658 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, self reported educational attainment and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Integrator complex subunit 9 |
|---|---|
| UniProt accession | Q9NV88 |
| Gene | INTS9 |
| Organism | Homo sapiens |
| Length | 658 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (38)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.27
- self reported educational attainment · score 0.22
- neoplasm · score 0.07
- hemoglobin E-beta-thalassemia syndrome · score 0.06
- hemoglobin D disease · score 0.05
- Adult-onset autosomal recessive sideroblastic anemia · score 0.05
- gluthathione peroxidase deficiency · score 0.05
- hemolytic anemia due to erythrocyte adenosine deaminase overproduction · score 0.04
- IRIDA syndrome · score 0.04
- pentosuria · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NV88-F1 | alphafold | PREDICTED | 90.94 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NV88.
Amino-acid sequence (658 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with INTS9?
The strongest Open Targets associations for INTS9 are neurodegenerative disease, self reported educational attainment, neoplasm, hemoglobin E-beta-thalassemia syndrome and hemoglobin D disease.
How long is the INTS9 protein?
The Homo sapiens INTS9 protein (UniProt Q9NV88) is 658 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NV88 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NV88 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.