Ubiquinol-cytochrome c reductase complex assembly factor 1 (UQCC1)
Homo sapiens — UniProt Q9NVA1
Data last refreshed: (UniProt release unknown)
Key facts
Ubiquinol-cytochrome c reductase complex assembly factor 1 (UQCC1) is a protein from Homo sapiens identified by UniProt accession Q9NVA1, 299 residues long. MolForge cross-references it against 0 known binders and 84 disease associations.
- UniProt accession: Q9NVA1; gene symbol UQCC1.
- Organism: Homo sapiens.
- Length: 299 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, BMI-adjusted waist-hip ratio and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ubiquinol-cytochrome c reductase complex assembly factor 1 |
|---|---|
| UniProt accession | Q9NVA1 |
| Gene | UQCC1 |
| Organism | Homo sapiens |
| Length | 299 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (84)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.55
- BMI-adjusted waist-hip ratio · score 0.46
- body height · score 0.44
- osteoarthritis, knee · score 0.42
- physical activity measurement · score 0.42
- appendicular lean mass · score 0.41
- waist-hip ratio · score 0.41
- vital capacity · score 0.40
- brain volume measurement · score 0.39
- cortical thickness · score 0.39
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NVA1-F1 | alphafold | PREDICTED | 74.37 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NVA1.
Amino-acid sequence (299 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UQCC1?
The strongest Open Targets associations for UQCC1 are neurodegenerative disease, BMI-adjusted waist-hip ratio, body height, osteoarthritis, knee and physical activity measurement.
How long is the UQCC1 protein?
The Homo sapiens UQCC1 protein (UniProt Q9NVA1) is 299 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NVA1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NVA1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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