Transmembrane protein 184C (TMEM184C)
Homo sapiens — UniProt Q9NVA4
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 184C (TMEM184C) is a protein from Homo sapiens identified by UniProt accession Q9NVA4, 438 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.
- UniProt accession: Q9NVA4; gene symbol TMEM184C.
- Organism: Homo sapiens.
- Length: 438 amino acids.
- Top disease associations (Open Targets): Neurodevelopmental abnormality, PHF-tau measurement and hypertension.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 184C |
|---|---|
| UniProt accession | Q9NVA4 |
| Gene | TMEM184C |
| Organism | Homo sapiens |
| Length | 438 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (56)
Diseases linked to this target (Open Targets).
- Neurodevelopmental abnormality · score 0.52
- PHF-tau measurement · score 0.25
- hypertension · score 0.24
- hemoglobin measurement · score 0.09
- platelet count · score 0.08
- erythrocyte count · score 0.08
- hematocrit · score 0.08
- red blood cell density measurement · score 0.07
- coronary artery disease · score 0.07
- angina pectoris · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NVA4-F1 | alphafold | PREDICTED | 71.50 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NVA4.
Amino-acid sequence (438 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM184C?
The strongest Open Targets associations for TMEM184C are Neurodevelopmental abnormality, PHF-tau measurement, hypertension, hemoglobin measurement and platelet count.
How long is the TMEM184C protein?
The Homo sapiens TMEM184C protein (UniProt Q9NVA4) is 438 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NVA4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NVA4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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