Alpha-parvin (PARVA)
Homo sapiens — UniProt Q9NVD7
Data last refreshed: (UniProt release unknown)
Key facts
Alpha-parvin (PARVA) is a protein from Homo sapiens identified by UniProt accession Q9NVD7, 372 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.
- UniProt accession: Q9NVD7; gene symbol PARVA.
- Organism: Homo sapiens.
- Length: 372 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, balding measurement and age-related hearing impairment.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Alpha-parvin |
|---|---|
| UniProt accession | Q9NVD7 |
| Gene | PARVA |
| Organism | Homo sapiens |
| Length | 372 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (63)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.49
- balding measurement · score 0.35
- age-related hearing impairment · score 0.29
- breast adenocarcinoma · score 0.23
- gut microbiome measurement · score 0.16
- body fat percentage · score 0.08
- resting heart rate · score 0.06
- Hepatic veno-occlusive disease - immunodeficiency · score 0.04
- amelogenesis imperfecta · score 0.04
- autoinflammation with episodic fever and lymphadenopathy · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NVD7-F1 | alphafold | PREDICTED | 79.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NVD7.
Amino-acid sequence (372 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PARVA?
The strongest Open Targets associations for PARVA are neurodegenerative disease, balding measurement, age-related hearing impairment, breast adenocarcinoma and gut microbiome measurement.
How long is the PARVA protein?
The Homo sapiens PARVA protein (UniProt Q9NVD7) is 372 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NVD7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NVD7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.