Coiled-coil domain-containing protein 87 (CCDC87)
Homo sapiens — UniProt Q9NVE4
Data last refreshed: (UniProt release unknown)
Key facts
Coiled-coil domain-containing protein 87 (CCDC87) is a protein from Homo sapiens identified by UniProt accession Q9NVE4, 849 residues long. MolForge cross-references it against 0 known binders and 94 disease associations.
- UniProt accession: Q9NVE4; gene symbol CCDC87.
- Organism: Homo sapiens.
- Length: 849 amino acids.
- Top disease associations (Open Targets): azoospermia, male infertility with teratozoospermia due to single gene mutation and fat body mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Coiled-coil domain-containing protein 87 |
|---|---|
| UniProt accession | Q9NVE4 |
| Gene | CCDC87 |
| Organism | Homo sapiens |
| Length | 849 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (94)
Diseases linked to this target (Open Targets).
- azoospermia · score 0.10
- male infertility with teratozoospermia due to single gene mutation · score 0.09
- fat body mass · score 0.07
- partial chromosome Y deletion · score 0.07
- spermatogenic failure 72 · score 0.07
- spermatogenic failure 27 · score 0.07
- spermatogenic failure 18 · score 0.07
- spermatogenic failure 46 · score 0.07
- spermatogenic failure 65 · score 0.07
- spermatogenic failure 49 · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NVE4-F1 | alphafold | PREDICTED | 62.15 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NVE4.
Amino-acid sequence (849 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CCDC87?
The strongest Open Targets associations for CCDC87 are azoospermia, male infertility with teratozoospermia due to single gene mutation, fat body mass, partial chromosome Y deletion and spermatogenic failure 72.
How long is the CCDC87 protein?
The Homo sapiens CCDC87 protein (UniProt Q9NVE4) is 849 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NVE4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NVE4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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