Ethanolamine kinase 2 (ETNK2)
Homo sapiens — UniProt Q9NVF9
Data last refreshed: (UniProt release unknown)
Key facts
Ethanolamine kinase 2 (ETNK2) is a protein from Homo sapiens identified by UniProt accession Q9NVF9, 386 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.
- UniProt accession: Q9NVF9; gene symbol ETNK2.
- Organism: Homo sapiens.
- Length: 386 amino acids.
- Top disease associations (Open Targets): optic cup area measurement, systolic blood pressure and testosterone measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ethanolamine kinase 2 |
|---|---|
| UniProt accession | Q9NVF9 |
| Gene | ETNK2 |
| Organism | Homo sapiens |
| Length | 386 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (38)
Diseases linked to this target (Open Targets).
- optic cup area measurement · score 0.29
- systolic blood pressure · score 0.25
- testosterone measurement · score 0.24
- breast adenocarcinoma · score 0.18
- papillary thyroid carcinoma · score 0.07
- gonorrhea · score 0.07
- hair shape measurement · score 0.04
- Barrett's esophagus · score 0.03
- neoplasm · score 0.02
- clear cell renal carcinoma · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NVF9-F1 | alphafold | PREDICTED | 87.70 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NVF9.
Amino-acid sequence (386 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ETNK2?
The strongest Open Targets associations for ETNK2 are optic cup area measurement, systolic blood pressure, testosterone measurement, breast adenocarcinoma and papillary thyroid carcinoma.
How long is the ETNK2 protein?
The Homo sapiens ETNK2 protein (UniProt Q9NVF9) is 386 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NVF9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NVF9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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