TBC1 domain family member 13 (TBC1D13)
Homo sapiens — UniProt Q9NVG8
Data last refreshed: (UniProt release unknown)
Key facts
TBC1 domain family member 13 (TBC1D13) is a protein from Homo sapiens identified by UniProt accession Q9NVG8, 400 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q9NVG8; gene symbol TBC1D13.
- Organism: Homo sapiens.
- Length: 400 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, high density lipoprotein cholesterol measurement and serum albumin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | TBC1 domain family member 13 |
|---|---|
| UniProt accession | Q9NVG8 |
| Gene | TBC1D13 |
| Organism | Homo sapiens |
| Length | 400 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.26
- high density lipoprotein cholesterol measurement · score 0.21
- serum albumin measurement · score 0.13
- BMI-adjusted waist-hip ratio · score 0.11
- blood metabolite measurement · score 0.11
- triglyceride measurement · score 0.10
- bilirubin measurement · score 0.05
- serum metabolite measurement · score 0.04
- BMI-adjusted waist circumference · score 0.03
- hypothyroidism · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NVG8-F1 | alphafold | PREDICTED | 88.12 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NVG8.
Amino-acid sequence (400 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TBC1D13?
The strongest Open Targets associations for TBC1D13 are neurodegenerative disease, high density lipoprotein cholesterol measurement, serum albumin measurement, BMI-adjusted waist-hip ratio and blood metabolite measurement.
How long is the TBC1D13 protein?
The Homo sapiens TBC1D13 protein (UniProt Q9NVG8) is 400 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NVG8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NVG8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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