DnaJ homolog subfamily C member 11 (DNAJC11)
Homo sapiens — UniProt Q9NVH1
Data last refreshed: (UniProt release unknown)
Key facts
DnaJ homolog subfamily C member 11 (DNAJC11) is a protein from Homo sapiens identified by UniProt accession Q9NVH1, 559 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.
- UniProt accession: Q9NVH1; gene symbol DNAJC11.
- Organism: Homo sapiens.
- Length: 559 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, heel bone mineral density and appendicular lean mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | DnaJ homolog subfamily C member 11 |
|---|---|
| UniProt accession | Q9NVH1 |
| Gene | DNAJC11 |
| Organism | Homo sapiens |
| Length | 559 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (56)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.20
- heel bone mineral density · score 0.18
- appendicular lean mass · score 0.16
- bone quantitative ultrasound measurement · score 0.16
- schizophrenia · score 0.14
- systolic blood pressure · score 0.13
- peak expiratory flow · score 0.11
- body fat percentage · score 0.10
- body mass index · score 0.09
- pulse pressure measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NVH1-F1 | alphafold | PREDICTED | 84.75 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NVH1.
Amino-acid sequence (559 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DNAJC11?
The strongest Open Targets associations for DNAJC11 are neurodegenerative disease, heel bone mineral density, appendicular lean mass, bone quantitative ultrasound measurement and schizophrenia.
How long is the DNAJC11 protein?
The Homo sapiens DNAJC11 protein (UniProt Q9NVH1) is 559 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NVH1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NVH1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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