Integrator complex subunit 7 (INTS7)
Homo sapiens — UniProt Q9NVH2
Data last refreshed: (UniProt release unknown)
Key facts
Integrator complex subunit 7 (INTS7) is a protein from Homo sapiens identified by UniProt accession Q9NVH2, 962 residues long. MolForge cross-references it against 0 known binders and 59 disease associations.
- UniProt accession: Q9NVH2; gene symbol INTS7.
- Organism: Homo sapiens.
- Length: 962 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, body height and appendicular lean mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Integrator complex subunit 7 |
|---|---|
| UniProt accession | Q9NVH2 |
| Gene | INTS7 |
| Organism | Homo sapiens |
| Length | 962 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (59)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.38
- body height · score 0.31
- appendicular lean mass · score 0.27
- lean body mass · score 0.24
- platelet count · score 0.24
- BMI-adjusted hip circumference · score 0.21
- platelet crit · score 0.19
- behavior or behavioral disorder measurement · score 0.19
- fat body mass · score 0.18
- birth weight · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NVH2-F1 | alphafold | PREDICTED | 88.07 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NVH2.
Amino-acid sequence (962 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with INTS7?
The strongest Open Targets associations for INTS7 are neurodegenerative disease, body height, appendicular lean mass, lean body mass and platelet count.
How long is the INTS7 protein?
The Homo sapiens INTS7 protein (UniProt Q9NVH2) is 962 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NVH2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NVH2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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