FGFR1 oncogene partner 2 (FGFR1OP2)
Homo sapiens — UniProt Q9NVK5
Data last refreshed: (UniProt release unknown)
Key facts
FGFR1 oncogene partner 2 (FGFR1OP2) is a protein from Homo sapiens identified by UniProt accession Q9NVK5, 253 residues long. MolForge cross-references it against 0 known binders and 90 disease associations.
- UniProt accession: Q9NVK5; gene symbol FGFR1OP2.
- Organism: Homo sapiens.
- Length: 253 amino acids.
- Top disease associations (Open Targets): cancer, neurodegenerative disease and acute lymphoblastic leukemia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | FGFR1 oncogene partner 2 |
|---|---|
| UniProt accession | Q9NVK5 |
| Gene | FGFR1OP2 |
| Organism | Homo sapiens |
| Length | 253 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (90)
Diseases linked to this target (Open Targets).
- cancer · score 0.57
- neurodegenerative disease · score 0.52
- acute lymphoblastic leukemia · score 0.46
- leukemia · score 0.46
- myelodysplastic syndrome · score 0.46
- chronic myelogenous leukemia · score 0.37
- basophil count · score 0.29
- basophil percentage of leukocytes · score 0.29
- breast adenocarcinoma · score 0.27
- endometrial cancer · score 0.26
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NVK5-F1 | alphafold | PREDICTED | 78.29 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NVK5.
Amino-acid sequence (253 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FGFR1OP2?
The strongest Open Targets associations for FGFR1OP2 are cancer, neurodegenerative disease, acute lymphoblastic leukemia, leukemia and myelodysplastic syndrome.
How long is the FGFR1OP2 protein?
The Homo sapiens FGFR1OP2 protein (UniProt Q9NVK5) is 253 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NVK5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NVK5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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