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Factor associated with metabolism and energy (CCDC198)

Homo sapiens — UniProt Q9NVL8

Gene: CCDC198Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Factor associated with metabolism and energy (CCDC198) is a protein from Homo sapiens identified by UniProt accession Q9NVL8, 296 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.

  • UniProt accession: Q9NVL8; gene symbol CCDC198.
  • Organism: Homo sapiens.
  • Length: 296 amino acids.
  • Top disease associations (Open Targets): self reported educational attainment, mathematical ability and lymphocyte count.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameFactor associated with metabolism and energy
UniProt accessionQ9NVL8
GeneCCDC198
OrganismHomo sapiens
Length296 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (12)

Diseases linked to this target (Open Targets).

  • self reported educational attainment · score 0.08
  • mathematical ability · score 0.06
  • lymphocyte count · score 0.06
  • Barrett's esophagus · score 0.05
  • esophageal adenocarcinoma · score 0.03
  • Colon Sessile Serrated Adenoma/Polyp · score 0.01
  • colorectal cancer · score 0.01
  • transitional cell carcinoma of kidney · score 0.01
  • non-small cell lung carcinoma · score 0.01
  • clear cell renal carcinoma · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9NVL8-F1alphafoldPREDICTED59.62—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NVL8.

Amino-acid sequence (296 residues)

MGLSHSKTHL RVIKVAPLQN KEVETPSAGR VDFAFNQNLE EKTSYSLARL QDQNKALEGQ LPPLQENWYG RYSTASRDMY FDIPLEHRET SIIKRHPPQR LQKLEPIDLP RVITSGRLLS QREARTMHKA KQVLEKKMQT PMYTSENRQY LHKMQVLEMI RKRQEAQMEL KKSLHGEARI NKQSPRDHKA KKTLQSTPRN DDHDLLTMLP DEILNRGPGN SKNTEFLKHQ AVNNYCPWKI GKMETWLHEQ EAQGQLLWDS SSSDSDEQGK DEKKPRALVR TRTERIPLFD EFFDQE

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CCDC198?

The strongest Open Targets associations for CCDC198 are self reported educational attainment, mathematical ability, lymphocyte count, Barrett's esophagus and esophageal adenocarcinoma.

How long is the CCDC198 protein?

The Homo sapiens CCDC198 protein (UniProt Q9NVL8) is 296 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9NVL8
GeneCCDC198
OrganismHomo sapiens
Length296
Binders0
Diseases12
View on UniProt