Protein eva-1 homolog B (EVA1B)
Homo sapiens — UniProt Q9NVM1
Data last refreshed: (UniProt release unknown)
Key facts
Protein eva-1 homolog B (EVA1B) is a protein from Homo sapiens identified by UniProt accession Q9NVM1, 165 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q9NVM1; gene symbol EVA1B.
- Organism: Homo sapiens.
- Length: 165 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, FEV/FVC ratio and appendicular lean mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein eva-1 homolog B |
|---|---|
| UniProt accession | Q9NVM1 |
| Gene | EVA1B |
| Organism | Homo sapiens |
| Length | 165 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.30
- FEV/FVC ratio · score 0.28
- appendicular lean mass · score 0.24
- body height · score 0.20
- lean body mass · score 0.18
- vital capacity · score 0.15
- type 2 diabetes mellitus · score 0.12
- fat body mass · score 0.11
- base metabolic rate measurement · score 0.10
- whole body water mass · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NVM1-F1 | alphafold | PREDICTED | 62.14 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NVM1.
Amino-acid sequence (165 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with EVA1B?
The strongest Open Targets associations for EVA1B are neurodegenerative disease, FEV/FVC ratio, appendicular lean mass, body height and lean body mass.
How long is the EVA1B protein?
The Homo sapiens EVA1B protein (UniProt Q9NVM1) is 165 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NVM1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NVM1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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