Protein eva-1 homolog B (EVA1B)

About Protein eva-1 homolog B

Protein eva-1 homolog B (EVA1B) is a protein from Homo sapiens identified by UniProt accession Q9NVM1, 165 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.

Target properties

Protein name	Protein eva-1 homolog B
UniProt accession	Q9NVM1
Gene	EVA1B
Organism	Homo sapiens
Length	165 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (24)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.30
FEV/FVC ratio · score 0.28
appendicular lean mass · score 0.24
body height · score 0.20
lean body mass · score 0.18
vital capacity · score 0.15
type 2 diabetes mellitus · score 0.12
fat body mass · score 0.11
base metabolic rate measurement · score 0.10
whole body water mass · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NVM1-F1	alphafold	PREDICTED	62.14	—

Amino-acid sequence (165 residues)

MDAPRRDMEL LSNSLAAYAH IRANPESFGL YFVLGVCFGL LLTLCLLVIS ISWAPRPRPR GPAQRRDPRS STLEPEDDDE DEEDTVTRLG PDDTLPGPEL SAEPDGPLNV NVFTSAEELE RAQRLEERER ILREIWRTGQ PDLLGTGTLG PSPTATGTLG RMHYY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards