Chaperone Ric-8B (RIC8B)
Homo sapiens — UniProt Q9NVN3
Data last refreshed: (UniProt release unknown)
Key facts
Chaperone Ric-8B (RIC8B) is a protein from Homo sapiens identified by UniProt accession Q9NVN3, 520 residues long. MolForge cross-references it against 0 known binders and 89 disease associations.
- UniProt accession: Q9NVN3; gene symbol RIC8B.
- Organism: Homo sapiens.
- Length: 520 amino acids.
- Top disease associations (Open Targets): triglyceride measurement, body height and cup-to-disc ratio measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Chaperone Ric-8B |
|---|---|
| UniProt accession | Q9NVN3 |
| Gene | RIC8B |
| Organism | Homo sapiens |
| Length | 520 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (89)
Diseases linked to this target (Open Targets).
- triglyceride measurement · score 0.35
- body height · score 0.32
- cup-to-disc ratio measurement · score 0.26
- sitting height measurement · score 0.26
- gut microbiome measurement · score 0.25
- BMI-adjusted hip circumference · score 0.19
- BMI-adjusted waist-hip ratio · score 0.19
- appendicular lean mass · score 0.18
- PR interval · score 0.17
- ankylosing spondylitis · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NVN3-F1 | alphafold | PREDICTED | 86.37 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NVN3.
Amino-acid sequence (520 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RIC8B?
The strongest Open Targets associations for RIC8B are triglyceride measurement, body height, cup-to-disc ratio measurement, sitting height measurement and gut microbiome measurement.
How long is the RIC8B protein?
The Homo sapiens RIC8B protein (UniProt Q9NVN3) is 520 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NVN3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NVN3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.