Androgen-induced gene 1 protein (AIG1)
Homo sapiens — UniProt Q9NVV5
Data last refreshed: (UniProt release unknown)
Key facts
Androgen-induced gene 1 protein (AIG1) is a protein from Homo sapiens identified by UniProt accession Q9NVV5, 238 residues long. MolForge cross-references it against 0 known binders and 63 disease associations.
- UniProt accession: Q9NVV5; gene symbol AIG1.
- Organism: Homo sapiens.
- Length: 238 amino acids.
- Top disease associations (Open Targets): alkaline phosphatase measurement, pulse pressure measurement and aortic measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Androgen-induced gene 1 protein |
|---|---|
| UniProt accession | Q9NVV5 |
| Gene | AIG1 |
| Organism | Homo sapiens |
| Length | 238 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (63)
Diseases linked to this target (Open Targets).
- alkaline phosphatase measurement · score 0.41
- pulse pressure measurement · score 0.40
- aortic measurement · score 0.37
- diastolic blood pressure · score 0.27
- common carotid intimal medial thickness · score 0.22
- Inguinal hernia · score 0.21
- Hernia of the abdominal wall · score 0.21
- lymphocyte count · score 0.10
- lobe attachment · score 0.08
- familial hypobetalipoproteinemia 2 · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NVV5-F1 | alphafold | PREDICTED | 93.82 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NVV5.
Amino-acid sequence (238 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AIG1?
The strongest Open Targets associations for AIG1 are alkaline phosphatase measurement, pulse pressure measurement, aortic measurement, diastolic blood pressure and common carotid intimal medial thickness.
How long is the AIG1 protein?
The Homo sapiens AIG1 protein (UniProt Q9NVV5) is 238 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NVV5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NVV5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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