Kelch repeat and BTB domain-containing protein 4 (KBTBD4)
Homo sapiens — UniProt Q9NVX7
Data last refreshed: (UniProt release unknown)
Key facts
Kelch repeat and BTB domain-containing protein 4 (KBTBD4) is a protein from Homo sapiens identified by UniProt accession Q9NVX7, 534 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.
- UniProt accession: Q9NVX7; gene symbol KBTBD4.
- Organism: Homo sapiens.
- Length: 534 amino acids.
- Top disease associations (Open Targets): lymphocyte count, myeloid white cell count and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Kelch repeat and BTB domain-containing protein 4 |
|---|---|
| UniProt accession | Q9NVX7 |
| Gene | KBTBD4 |
| Organism | Homo sapiens |
| Length | 534 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (56)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.06
- myeloid white cell count · score 0.06
- neoplasm · score 0.05
- body fat distribution · score 0.05
- grip strength measurement · score 0.05
- neuroimaging measurement · score 0.04
- diet measurement · score 0.04
- age at menarche · score 0.04
- high density lipoprotein cholesterol measurement · score 0.04
- body weight · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NVX7-F1 | alphafold | PREDICTED | 77.71 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NVX7.
Amino-acid sequence (534 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KBTBD4?
The strongest Open Targets associations for KBTBD4 are lymphocyte count, myeloid white cell count, neoplasm, body fat distribution and grip strength measurement.
How long is the KBTBD4 protein?
The Homo sapiens KBTBD4 protein (UniProt Q9NVX7) is 534 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NVX7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NVX7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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