Anoctamin-10 (ANO10)
Homo sapiens — UniProt Q9NW15
Data last refreshed: (UniProt release unknown)
Key facts
Anoctamin-10 (ANO10) is a protein from Homo sapiens identified by UniProt accession Q9NW15, 660 residues long. MolForge cross-references it against 0 known binders and 70 disease associations.
- UniProt accession: Q9NW15; gene symbol ANO10.
- Organism: Homo sapiens.
- Length: 660 amino acids.
- Top disease associations (Open Targets): autosomal recessive spinocerebellar ataxia 10, Adult-onset autosomal recessive cerebellar ataxia and Dorfman-Chanarin disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Anoctamin-10 |
|---|---|
| UniProt accession | Q9NW15 |
| Gene | ANO10 |
| Organism | Homo sapiens |
| Length | 660 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (70)
Diseases linked to this target (Open Targets).
- autosomal recessive spinocerebellar ataxia 10 · score 0.72
- Adult-onset autosomal recessive cerebellar ataxia · score 0.70
- Dorfman-Chanarin disease · score 0.47
- autosomal recessive cerebellar ataxia · score 0.40
- COVID-19 · score 0.37
- protein measurement · score 0.35
- Abnormal central motor function · score 0.34
- genetic disorder · score 0.19
- BMI-adjusted waist-hip ratio · score 0.19
- BMI-adjusted waist circumference · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NW15-F1 | alphafold | PREDICTED | 86.12 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NW15.
Amino-acid sequence (660 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ANO10?
The strongest Open Targets associations for ANO10 are autosomal recessive spinocerebellar ataxia 10, Adult-onset autosomal recessive cerebellar ataxia, Dorfman-Chanarin disease, autosomal recessive cerebellar ataxia and COVID-19.
How long is the ANO10 protein?
The Homo sapiens ANO10 protein (UniProt Q9NW15) is 660 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NW15 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NW15 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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