Distal membrane-arm assembly complex protein 2 (DMAC2)
Homo sapiens — UniProt Q9NW81
Data last refreshed: (UniProt release unknown)
Key facts
Distal membrane-arm assembly complex protein 2 (DMAC2) is a protein from Homo sapiens identified by UniProt accession Q9NW81, 257 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q9NW81; gene symbol DMAC2.
- Organism: Homo sapiens.
- Length: 257 amino acids.
- Top disease associations (Open Targets): blood protein measurement, body height and appendicular lean mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Distal membrane-arm assembly complex protein 2 |
|---|---|
| UniProt accession | Q9NW81 |
| Gene | DMAC2 |
| Organism | Homo sapiens |
| Length | 257 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.18
- body height · score 0.16
- appendicular lean mass · score 0.09
- hair shape measurement · score 0.09
- lean body mass · score 0.07
- BMI-adjusted waist circumference · score 0.07
- balding measurement · score 0.07
- BMI-adjusted hip circumference · score 0.07
- Red cell distribution width · score 0.07
- prostate carcinoma · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NW81-F1 | alphafold | PREDICTED | 79.17 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NW81.
Amino-acid sequence (257 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DMAC2?
The strongest Open Targets associations for DMAC2 are blood protein measurement, body height, appendicular lean mass, hair shape measurement and lean body mass.
How long is the DMAC2 protein?
The Homo sapiens DMAC2 protein (UniProt Q9NW81) is 257 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NW81 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NW81 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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