Arginine and glutamate-rich protein 1 (ARGLU1)
Homo sapiens — UniProt Q9NWB6
Data last refreshed: (UniProt release unknown)
Key facts
Arginine and glutamate-rich protein 1 (ARGLU1) is a protein from Homo sapiens identified by UniProt accession Q9NWB6, 273 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.
- UniProt accession: Q9NWB6; gene symbol ARGLU1.
- Organism: Homo sapiens.
- Length: 273 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, serum alanine aminotransferase measurement and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Arginine and glutamate-rich protein 1 |
|---|---|
| UniProt accession | Q9NWB6 |
| Gene | ARGLU1 |
| Organism | Homo sapiens |
| Length | 273 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (41)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.52
- serum alanine aminotransferase measurement · score 0.30
- platelet count · score 0.18
- gut microbiome measurement · score 0.16
- mean platelet volume · score 0.15
- cortical thickness · score 0.12
- adolescent idiopathic scoliosis · score 0.11
- cognitive function measurement · score 0.11
- cortical surface area measurement · score 0.10
- brain measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NWB6-F1 | alphafold | PREDICTED | 74.93 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NWB6.
Amino-acid sequence (273 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ARGLU1?
The strongest Open Targets associations for ARGLU1 are neurodegenerative disease, serum alanine aminotransferase measurement, platelet count, gut microbiome measurement and mean platelet volume.
How long is the ARGLU1 protein?
The Homo sapiens ARGLU1 protein (UniProt Q9NWB6) is 273 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NWB6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NWB6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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