Box C/D snoRNA protein 1 (ZNHIT6)
Homo sapiens — UniProt Q9NWK9
Data last refreshed: (UniProt release unknown)
Key facts
Box C/D snoRNA protein 1 (ZNHIT6) is a protein from Homo sapiens identified by UniProt accession Q9NWK9, 470 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.
- UniProt accession: Q9NWK9; gene symbol ZNHIT6.
- Organism: Homo sapiens.
- Length: 470 amino acids.
- Top disease associations (Open Targets): BMI-adjusted waist-hip ratio, BMI-adjusted waist circumference and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Box C/D snoRNA protein 1 |
|---|---|
| UniProt accession | Q9NWK9 |
| Gene | ZNHIT6 |
| Organism | Homo sapiens |
| Length | 470 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- BMI-adjusted waist-hip ratio · score 0.22
- BMI-adjusted waist circumference · score 0.12
- body height · score 0.09
- waist-hip ratio · score 0.08
- grip strength measurement · score 0.04
- immunodeficiency 75 · score 0.03
- Kimura disease · score 0.03
- Hepatic veno-occlusive disease - immunodeficiency · score 0.03
- esophageal squamous cell carcinoma · score 0.03
- waist circumference · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NWK9-F1 | alphafold | PREDICTED | 60.01 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NWK9.
Amino-acid sequence (470 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNHIT6?
The strongest Open Targets associations for ZNHIT6 are BMI-adjusted waist-hip ratio, BMI-adjusted waist circumference, body height, waist-hip ratio and grip strength measurement.
How long is the ZNHIT6 protein?
The Homo sapiens ZNHIT6 protein (UniProt Q9NWK9) is 470 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NWK9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NWK9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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