Asparagine synthetase domain-containing protein 1 (ASNSD1)
Homo sapiens — UniProt Q9NWL6
Data last refreshed: (UniProt release unknown)
Key facts
Asparagine synthetase domain-containing protein 1 (ASNSD1) is a protein from Homo sapiens identified by UniProt accession Q9NWL6, 643 residues long. MolForge cross-references it against 0 known binders and 196 disease associations.
- UniProt accession: Q9NWL6; gene symbol ASNSD1.
- Organism: Homo sapiens.
- Length: 643 amino acids.
- Top disease associations (Open Targets): liver iron measurement, Red cell distribution width and myopathy.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Asparagine synthetase domain-containing protein 1 |
|---|---|
| UniProt accession | Q9NWL6 |
| Gene | ASNSD1 |
| Organism | Homo sapiens |
| Length | 643 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (196)
Diseases linked to this target (Open Targets).
- liver iron measurement · score 0.17
- Red cell distribution width · score 0.15
- myopathy · score 0.07
- myofibrillar myopathy 3 · score 0.06
- Distal myotilinopathy · score 0.06
- Congenital myasthenic syndromes · score 0.06
- GNE myopathy · score 0.06
- tibial muscular dystrophy · score 0.06
- Distal myopathy, Nonaka type · score 0.06
- autosomal recessive limb-girdle muscular dystrophy type 2L · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NWL6-F1 | alphafold | PREDICTED | 85.72 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NWL6.
Amino-acid sequence (643 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ASNSD1?
The strongest Open Targets associations for ASNSD1 are liver iron measurement, Red cell distribution width, myopathy, myofibrillar myopathy 3 and Distal myotilinopathy.
How long is the ASNSD1 protein?
The Homo sapiens ASNSD1 protein (UniProt Q9NWL6) is 643 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NWL6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NWL6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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