F-box only protein 34 (FBXO34)
Homo sapiens — UniProt Q9NWN3
Data last refreshed: (UniProt release unknown)
Key facts
F-box only protein 34 (FBXO34) is a protein from Homo sapiens identified by UniProt accession Q9NWN3, 711 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.
- UniProt accession: Q9NWN3; gene symbol FBXO34.
- Organism: Homo sapiens.
- Length: 711 amino acids.
- Top disease associations (Open Targets): mean platelet volume, eosinophil count and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | F-box only protein 34 |
|---|---|
| UniProt accession | Q9NWN3 |
| Gene | FBXO34 |
| Organism | Homo sapiens |
| Length | 711 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (31)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.49
- eosinophil count · score 0.46
- platelet count · score 0.45
- blood protein measurement · score 0.44
- Red cell distribution width · score 0.43
- reticulocyte measurement · score 0.38
- reticulocyte count · score 0.38
- Immature Reticulocyte Fraction Measurement · score 0.37
- galectin-3 measurement · score 0.36
- eosinophil percentage of leukocytes · score 0.35
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NWN3-F1 | alphafold | PREDICTED | 48.72 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NWN3.
Amino-acid sequence (711 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FBXO34?
The strongest Open Targets associations for FBXO34 are mean platelet volume, eosinophil count, platelet count, blood protein measurement and Red cell distribution width.
How long is the FBXO34 protein?
The Homo sapiens FBXO34 protein (UniProt Q9NWN3) is 711 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NWN3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NWN3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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