G patch domain-containing protein 2-like (GPATCH2L)
Homo sapiens — UniProt Q9NWQ4
Data last refreshed: (UniProt release unknown)
Key facts
G patch domain-containing protein 2-like (GPATCH2L) is a protein from Homo sapiens identified by UniProt accession Q9NWQ4, 482 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: Q9NWQ4; gene symbol GPATCH2L.
- Organism: Homo sapiens.
- Length: 482 amino acids.
- Top disease associations (Open Targets): hemoglobin measurement, hematocrit and FEV/FVC ratio.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | G patch domain-containing protein 2-like |
|---|---|
| UniProt accession | Q9NWQ4 |
| Gene | GPATCH2L |
| Organism | Homo sapiens |
| Length | 482 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- hemoglobin measurement · score 0.47
- hematocrit · score 0.41
- FEV/FVC ratio · score 0.38
- erythrocyte count · score 0.31
- mean corpuscular hemoglobin concentration · score 0.30
- adolescent idiopathic scoliosis · score 0.28
- Alzheimer disease · score 0.01
- Pick disease · score 0.01
- type 1 diabetes mellitus · score 0.01
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NWQ4-F1 | alphafold | PREDICTED | 50.99 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NWQ4.
Amino-acid sequence (482 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GPATCH2L?
The strongest Open Targets associations for GPATCH2L are hemoglobin measurement, hematocrit, FEV/FVC ratio, erythrocyte count and mean corpuscular hemoglobin concentration.
How long is the GPATCH2L protein?
The Homo sapiens GPATCH2L protein (UniProt Q9NWQ4) is 482 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NWQ4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NWQ4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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