Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (PAG1)
Homo sapiens — UniProt Q9NWQ8
Data last refreshed: (UniProt release unknown)
Key facts
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (PAG1) is a protein from Homo sapiens identified by UniProt accession Q9NWQ8, 432 residues long. MolForge cross-references it against 0 known binders and 79 disease associations.
- UniProt accession: Q9NWQ8; gene symbol PAG1.
- Organism: Homo sapiens.
- Length: 432 amino acids.
- Top disease associations (Open Targets): monocyte count, total blood protein measurement and diet measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 |
|---|---|
| UniProt accession | Q9NWQ8 |
| Gene | PAG1 |
| Organism | Homo sapiens |
| Length | 432 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (79)
Diseases linked to this target (Open Targets).
- monocyte count · score 0.35
- total blood protein measurement · score 0.32
- diet measurement · score 0.27
- PHF-tau measurement · score 0.27
- monocyte percentage of leukocytes · score 0.25
- blood protein measurement · score 0.24
- breast adenocarcinoma · score 0.23
- protein measurement · score 0.20
- sex hormone-binding globulin measurement · score 0.17
- mean corpuscular volume · score 0.11
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NWQ8-F1 | alphafold | PREDICTED | 54.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NWQ8.
Amino-acid sequence (432 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PAG1?
The strongest Open Targets associations for PAG1 are monocyte count, total blood protein measurement, diet measurement, PHF-tau measurement and monocyte percentage of leukocytes.
How long is the PAG1 protein?
The Homo sapiens PAG1 protein (UniProt Q9NWQ8) is 432 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NWQ8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NWQ8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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