Uncharacterized protein C14orf119 (C14orf119)
Homo sapiens — UniProt Q9NWQ9
Data last refreshed: (UniProt release unknown)
Key facts
Uncharacterized protein C14orf119 (C14orf119) is a protein from Homo sapiens identified by UniProt accession Q9NWQ9, 140 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.
- UniProt accession: Q9NWQ9; gene symbol C14orf119.
- Organism: Homo sapiens.
- Length: 140 amino acids.
- Top disease associations (Open Targets): mean reticulocyte volume, hemochromatosis type 5 and FTH1-related iron overload.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Uncharacterized protein C14orf119 |
|---|---|
| UniProt accession | Q9NWQ9 |
| Gene | C14orf119 |
| Organism | Homo sapiens |
| Length | 140 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (17)
Diseases linked to this target (Open Targets).
- mean reticulocyte volume · score 0.07
- hemochromatosis type 5 · score 0.05
- FTH1-related iron overload · score 0.05
- basophil count · score 0.03
- hereditary hyperferritinemia with congenital cataracts · score 0.03
- eosinophil count · score 0.02
- Alzheimer disease · score 0.01
- pancreatic adenocarcinoma · score 0.01
- Neurodevelopmental delay · score 0.01
- hepatocellular carcinoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NWQ9-F1 | alphafold | PREDICTED | 78.91 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NWQ9.
Amino-acid sequence (140 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C14orf119?
The strongest Open Targets associations for C14orf119 are mean reticulocyte volume, hemochromatosis type 5, FTH1-related iron overload, basophil count and hereditary hyperferritinemia with congenital cataracts.
How long is the C14orf119 protein?
The Homo sapiens C14orf119 protein (UniProt Q9NWQ9) is 140 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NWQ9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NWQ9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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