p21-activated protein kinase-interacting protein 1 (PAK1IP1)
Homo sapiens — UniProt Q9NWT1
Data last refreshed: (UniProt release unknown)
Key facts
p21-activated protein kinase-interacting protein 1 (PAK1IP1) is a protein from Homo sapiens identified by UniProt accession Q9NWT1, 392 residues long. MolForge cross-references it against 0 known binders and 17 disease associations.
- UniProt accession: Q9NWT1; gene symbol PAK1IP1.
- Organism: Homo sapiens.
- Length: 392 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, hair colour measurement and monocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | p21-activated protein kinase-interacting protein 1 |
|---|---|
| UniProt accession | Q9NWT1 |
| Gene | PAK1IP1 |
| Organism | Homo sapiens |
| Length | 392 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (17)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.47
- hair colour measurement · score 0.04
- monocyte count · score 0.03
- monocyte percentage of leukocytes · score 0.03
- hepatocellular carcinoma · score 0.03
- urate measurement · score 0.02
- leukocyte count · score 0.02
- colorectal cancer · score 0.01
- orofacial cleft · score 0.01
- Huntington disease · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NWT1-F1 | alphafold | PREDICTED | 80.99 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NWT1.
Amino-acid sequence (392 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PAK1IP1?
The strongest Open Targets associations for PAK1IP1 are neurodegenerative disease, hair colour measurement, monocyte count, monocyte percentage of leukocytes and hepatocellular carcinoma.
How long is the PAK1IP1 protein?
The Homo sapiens PAK1IP1 protein (UniProt Q9NWT1) is 392 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NWT1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NWT1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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