Small ribosomal subunit protein bS22, mitochondrial (AURKAIP1)
Homo sapiens — UniProt Q9NWT8
Data last refreshed: (UniProt release unknown)
Key facts
Small ribosomal subunit protein bS22, mitochondrial (AURKAIP1) is a protein from Homo sapiens identified by UniProt accession Q9NWT8, 199 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q9NWT8; gene symbol AURKAIP1.
- Organism: Homo sapiens.
- Length: 199 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, osteoporosis and systolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Small ribosomal subunit protein bS22, mitochondrial |
|---|---|
| UniProt accession | Q9NWT8 |
| Gene | AURKAIP1 |
| Organism | Homo sapiens |
| Length | 199 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.20
- osteoporosis · score 0.11
- systolic blood pressure · score 0.10
- heel bone mineral density · score 0.09
- peak expiratory flow · score 0.08
- triple-negative breast cancer · score 0.07
- intraocular pressure measurement · score 0.07
- Drugs affecting bone structure and mineralization use measurement · score 0.05
- sitting height measurement · score 0.05
- eosinophil count · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NWT8-F1 | alphafold | PREDICTED | 67.71 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NWT8.
Amino-acid sequence (199 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AURKAIP1?
The strongest Open Targets associations for AURKAIP1 are neurodegenerative disease, osteoporosis, systolic blood pressure, heel bone mineral density and peak expiratory flow.
How long is the AURKAIP1 protein?
The Homo sapiens AURKAIP1 protein (UniProt Q9NWT8) is 199 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NWT8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NWT8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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