3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial (OXSM)
Homo sapiens — UniProt Q9NWU1
Data last refreshed: (UniProt release unknown)
Key facts
3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial (OXSM) is a protein from Homo sapiens identified by UniProt accession Q9NWU1, 459 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.
- UniProt accession: Q9NWU1; gene symbol OXSM.
- Organism: Homo sapiens.
- Length: 459 amino acids.
- Top disease associations (Open Targets): congenital disorder of deglycosylation, genetic disorder and congenital disorder of deglycosylation 1.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial |
|---|---|
| UniProt accession | Q9NWU1 |
| Gene | OXSM |
| Organism | Homo sapiens |
| Length | 459 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (43)
Diseases linked to this target (Open Targets).
- congenital disorder of deglycosylation · score 0.51
- genetic disorder · score 0.39
- congenital disorder of deglycosylation 1 · score 0.29
- neurodegenerative disease · score 0.29
- DNA methylation · score 0.15
- total blood protein measurement · score 0.15
- insomnia · score 0.15
- deafness · score 0.06
- alcohol drinking · score 0.06
- glioblastoma multiforme · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NWU1-F1 | alphafold | PREDICTED | 94.33 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NWU1.
Amino-acid sequence (459 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OXSM?
The strongest Open Targets associations for OXSM are congenital disorder of deglycosylation, genetic disorder, congenital disorder of deglycosylation 1, neurodegenerative disease and DNA methylation.
How long is the OXSM protein?
The Homo sapiens OXSM protein (UniProt Q9NWU1) is 459 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NWU1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NWU1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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