Glucose-induced degradation protein 8 homolog (GID8)
Homo sapiens — UniProt Q9NWU2
Data last refreshed: (UniProt release unknown)
Key facts
Glucose-induced degradation protein 8 homolog (GID8) is a protein from Homo sapiens identified by UniProt accession Q9NWU2, 228 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.
- UniProt accession: Q9NWU2; gene symbol GID8.
- Organism: Homo sapiens.
- Length: 228 amino acids.
- Top disease associations (Open Targets): body weight, lean body mass and monocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Glucose-induced degradation protein 8 homolog |
|---|---|
| UniProt accession | Q9NWU2 |
| Gene | GID8 |
| Organism | Homo sapiens |
| Length | 228 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (26)
Diseases linked to this target (Open Targets).
- body weight · score 0.14
- lean body mass · score 0.12
- monocyte count · score 0.11
- fat body mass · score 0.11
- mean corpuscular volume · score 0.10
- base metabolic rate measurement · score 0.09
- monocyte percentage of leukocytes · score 0.08
- whole body water mass · score 0.08
- hip circumference · score 0.08
- serum gamma-glutamyl transferase measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NWU2-F1 | alphafold | PREDICTED | 91.96 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NWU2.
Amino-acid sequence (228 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GID8?
The strongest Open Targets associations for GID8 are body weight, lean body mass, monocyte count, fat body mass and mean corpuscular volume.
How long is the GID8 protein?
The Homo sapiens GID8 protein (UniProt Q9NWU2) is 228 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NWU2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NWU2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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