CXXC motif containing zinc binding protein (CZIB)
Homo sapiens — UniProt Q9NWV4
Data last refreshed: (UniProt release unknown)
Key facts
CXXC motif containing zinc binding protein (CZIB) is a protein from Homo sapiens identified by UniProt accession Q9NWV4, 160 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q9NWV4; gene symbol CZIB.
- Organism: Homo sapiens.
- Length: 160 amino acids.
- Top disease associations (Open Targets): carnitine palmitoyltransferase II deficiency, urinary metabolite measurement and serum metabolite measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | CXXC motif containing zinc binding protein |
|---|---|
| UniProt accession | Q9NWV4 |
| Gene | CZIB |
| Organism | Homo sapiens |
| Length | 160 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- carnitine palmitoyltransferase II deficiency · score 0.12
- urinary metabolite measurement · score 0.11
- serum metabolite measurement · score 0.08
- blood metabolite measurement · score 0.07
- brain volume measurement · score 0.06
- protein measurement · score 0.06
- emotional symptom measurement · score 0.05
- feeling emotionally hurt measurement · score 0.04
- acylcarnitine measurement · score 0.03
- brain measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NWV4-F1 | alphafold | PREDICTED | 96.99 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NWV4.
Amino-acid sequence (160 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CZIB?
The strongest Open Targets associations for CZIB are carnitine palmitoyltransferase II deficiency, urinary metabolite measurement, serum metabolite measurement, blood metabolite measurement and brain volume measurement.
How long is the CZIB protein?
The Homo sapiens CZIB protein (UniProt Q9NWV4) is 160 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NWV4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NWV4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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