BRISC and BRCA1-A complex member 1 (BABAM1)
Homo sapiens — UniProt Q9NWV8
Data last refreshed: (UniProt release unknown)
Key facts
BRISC and BRCA1-A complex member 1 (BABAM1) is a protein from Homo sapiens identified by UniProt accession Q9NWV8, 329 residues long. MolForge cross-references it against 0 known binders and 59 disease associations.
- UniProt accession: Q9NWV8; gene symbol BABAM1.
- Organism: Homo sapiens.
- Length: 329 amino acids.
- Top disease associations (Open Targets): ovarian cancer, breast adenocarcinoma and squamous cell lung carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | BRISC and BRCA1-A complex member 1 |
|---|---|
| UniProt accession | Q9NWV8 |
| Gene | BABAM1 |
| Organism | Homo sapiens |
| Length | 329 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (59)
Diseases linked to this target (Open Targets).
- ovarian cancer · score 0.28
- breast adenocarcinoma · score 0.28
- squamous cell lung carcinoma · score 0.24
- acute myeloid leukemia · score 0.15
- breast carcinoma · score 0.13
- ovarian carcinoma · score 0.08
- estrogen-receptor negative breast cancer · score 0.08
- malignant epithelial tumor of ovary · score 0.07
- triple-negative breast cancer · score 0.06
- diastolic blood pressure · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NWV8-F1 | alphafold | PREDICTED | 78.16 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NWV8.
Amino-acid sequence (329 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BABAM1?
The strongest Open Targets associations for BABAM1 are ovarian cancer, breast adenocarcinoma, squamous cell lung carcinoma, acute myeloid leukemia and breast carcinoma.
How long is the BABAM1 protein?
The Homo sapiens BABAM1 protein (UniProt Q9NWV8) is 329 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NWV8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NWV8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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