Nicotinamide riboside kinase 1 (NMRK1)
Homo sapiens — UniProt Q9NWW6
Data last refreshed: (UniProt release unknown)
Key facts
Nicotinamide riboside kinase 1 (NMRK1) is a protein from Homo sapiens identified by UniProt accession Q9NWW6, 199 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.
- UniProt accession: Q9NWW6; gene symbol NMRK1.
- Organism: Homo sapiens.
- Length: 199 amino acids.
- Top disease associations (Open Targets): adolescent idiopathic scoliosis, metabolite measurement and loneliness measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Nicotinamide riboside kinase 1 |
|---|---|
| UniProt accession | Q9NWW6 |
| Gene | NMRK1 |
| Organism | Homo sapiens |
| Length | 199 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (40)
Diseases linked to this target (Open Targets).
- adolescent idiopathic scoliosis · score 0.18
- metabolite measurement · score 0.12
- loneliness measurement · score 0.09
- basophil count · score 0.08
- apolipoprotein B measurement · score 0.06
- Neck pain · score 0.05
- Shoulder pain · score 0.05
- alcohol consumption measurement · score 0.04
- wellbeing measurement · score 0.04
- calcium measurement · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NWW6-F1 | alphafold | PREDICTED | 93.70 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NWW6.
Amino-acid sequence (199 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NMRK1?
The strongest Open Targets associations for NMRK1 are adolescent idiopathic scoliosis, metabolite measurement, loneliness measurement, basophil count and apolipoprotein B measurement.
How long is the NMRK1 protein?
The Homo sapiens NMRK1 protein (UniProt Q9NWW6) is 199 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NWW6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NWW6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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