Nicotinamide riboside kinase 1 (NMRK1)

About Nicotinamide riboside kinase 1

Nicotinamide riboside kinase 1 (NMRK1) is a protein from Homo sapiens identified by UniProt accession Q9NWW6, 199 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.

Target properties

Protein name	Nicotinamide riboside kinase 1
UniProt accession	Q9NWW6
Gene	NMRK1
Organism	Homo sapiens
Length	199 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (40)

Diseases linked to this target (Open Targets).

adolescent idiopathic scoliosis · score 0.18
metabolite measurement · score 0.12
loneliness measurement · score 0.09
basophil count · score 0.08
apolipoprotein B measurement · score 0.06
Neck pain · score 0.05
Shoulder pain · score 0.05
alcohol consumption measurement · score 0.04
wellbeing measurement · score 0.04
calcium measurement · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NWW6-F1	alphafold	PREDICTED	93.70	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NWW6.

Amino-acid sequence (199 residues)

MKTFIIGISG VTNSGKTTLA KNLQKHLPNC SVISQDDFFK PESEIETDKN GFLQYDVLEA LNMEKMMSAI SCWMESARHS VVSTDQESAE EIPILIIEGF LLFNYKPLDT IWNRSYFLTI PYEECKRRRS TRVYQPPDSP GYFDGHVWPM YLKYRQEMQD ITWEVVYLDG TKSEEDLFLQ VYEDLIQELA KQKCLQVTA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards