Phospholipase A and acyltransferase 2 (PLAAT2)
Homo sapiens — UniProt Q9NWW9
Data last refreshed: (UniProt release unknown)
Key facts
Phospholipase A and acyltransferase 2 (PLAAT2) is a protein from Homo sapiens identified by UniProt accession Q9NWW9, 162 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.
- UniProt accession: Q9NWW9; gene symbol PLAAT2.
- Organism: Homo sapiens.
- Length: 162 amino acids.
- Top disease associations (Open Targets): urate measurement, uric acid measurement and Barrett's esophagus.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Phospholipase A and acyltransferase 2 |
|---|---|
| UniProt accession | Q9NWW9 |
| Gene | PLAAT2 |
| Organism | Homo sapiens |
| Length | 162 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (26)
Diseases linked to this target (Open Targets).
- urate measurement · score 0.19
- uric acid measurement · score 0.13
- Barrett's esophagus · score 0.06
- esophageal adenocarcinoma · score 0.04
- colorectal cancer · score 0.02
- colorectal adenocarcinoma · score 0.02
- gastric carcinoma · score 0.01
- clear cell renal carcinoma · score 0.01
- COVID-19 · score 0.01
- chronic kidney disease · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NWW9-F1 | alphafold | PREDICTED | 77.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NWW9.
Amino-acid sequence (162 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PLAAT2?
The strongest Open Targets associations for PLAAT2 are urate measurement, uric acid measurement, Barrett's esophagus, esophageal adenocarcinoma and colorectal cancer.
How long is the PLAAT2 protein?
The Homo sapiens PLAAT2 protein (UniProt Q9NWW9) is 162 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NWW9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NWW9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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