Ankyrin repeat and SOCS box protein 6 (ASB6)
Homo sapiens — UniProt Q9NWX5
Data last refreshed: (UniProt release unknown)
Key facts
Ankyrin repeat and SOCS box protein 6 (ASB6) is a protein from Homo sapiens identified by UniProt accession Q9NWX5, 421 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q9NWX5; gene symbol ASB6.
- Organism: Homo sapiens.
- Length: 421 amino acids.
- Top disease associations (Open Targets): clear cell renal carcinoma, pancreatic adenocarcinoma and body height.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ankyrin repeat and SOCS box protein 6 |
|---|---|
| UniProt accession | Q9NWX5 |
| Gene | ASB6 |
| Organism | Homo sapiens |
| Length | 421 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- clear cell renal carcinoma · score 0.18
- pancreatic adenocarcinoma · score 0.18
- body height · score 0.12
- sitting height measurement · score 0.09
- serum alanine aminotransferase measurement · score 0.09
- arterial stiffness measurement · score 0.04
- oral squamous cell carcinoma · score 0.04
- cancer · score 0.04
- protein measurement · score 0.04
- neoplasm · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NWX5-F1 | alphafold | PREDICTED | 87.13 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NWX5.
Amino-acid sequence (421 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ASB6?
The strongest Open Targets associations for ASB6 are clear cell renal carcinoma, pancreatic adenocarcinoma, body height, sitting height measurement and serum alanine aminotransferase measurement.
How long is the ASB6 protein?
The Homo sapiens ASB6 protein (UniProt Q9NWX5) is 421 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NWX5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NWX5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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