Gem-associated protein 8 (GEMIN8)
Homo sapiens — UniProt Q9NWZ8
Data last refreshed: (UniProt release unknown)
Key facts
Gem-associated protein 8 (GEMIN8) is a protein from Homo sapiens identified by UniProt accession Q9NWZ8, 242 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.
- UniProt accession: Q9NWZ8; gene symbol GEMIN8.
- Organism: Homo sapiens.
- Length: 242 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, severe malarial anemia and psoriasis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Gem-associated protein 8 |
|---|---|
| UniProt accession | Q9NWZ8 |
| Gene | GEMIN8 |
| Organism | Homo sapiens |
| Length | 242 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (5)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- severe malarial anemia · score 0.01
- psoriasis · score 0.01
- neoplasm · score 0.00
- axial length measurement · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NWZ8-F1 | alphafold | PREDICTED | 68.63 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NWZ8.
Amino-acid sequence (242 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GEMIN8?
The strongest Open Targets associations for GEMIN8 are neurodegenerative disease, severe malarial anemia, psoriasis, neoplasm and axial length measurement.
How long is the GEMIN8 protein?
The Homo sapiens GEMIN8 protein (UniProt Q9NWZ8) is 242 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NWZ8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NWZ8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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