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Transmembrane protein 160 (TMEM160)

Homo sapiens — UniProt Q9NX00

Gene: TMEM160Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Transmembrane protein 160 (TMEM160) is a protein from Homo sapiens identified by UniProt accession Q9NX00, 188 residues long. MolForge cross-references it against 0 known binders and 64 disease associations.

  • UniProt accession: Q9NX00; gene symbol TMEM160.
  • Organism: Homo sapiens.
  • Length: 188 amino acids.
  • Top disease associations (Open Targets): cognitive function measurement, intelligence and body mass index.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameTransmembrane protein 160
UniProt accessionQ9NX00
GeneTMEM160
OrganismHomo sapiens
Length188 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (64)

Diseases linked to this target (Open Targets).

  • cognitive function measurement · score 0.27
  • intelligence · score 0.23
  • body mass index · score 0.22
  • body fat distribution · score 0.22
  • self reported educational attainment · score 0.20
  • verbal-numerical reasoning measurement · score 0.20
  • diastolic blood pressure · score 0.19
  • high density lipoprotein cholesterol measurement · score 0.17
  • sex hormone-binding globulin measurement · score 0.16
  • apolipoprotein A 1 measurement · score 0.15

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9NX00-F1alphafoldPREDICTED75.85—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NX00.

Amino-acid sequence (188 residues)

MGGGWWWARA ARLARLRFRR SLLPPQRPRS GGARGSFAPG HGPRAGASPP PVSELDRADA WLLRKAHETA FLSWFRNGLL ASGIGVISFM QSDMGREAAY GFFLLGGLCV VWGSASYAVG LAALRGPMQL TLGGAAVGAG AVLAASLLWA CAVGLYMGQL ELDVELVPED DGTASAEGPD EAGRPPPE

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with TMEM160?

The strongest Open Targets associations for TMEM160 are cognitive function measurement, intelligence, body mass index, body fat distribution and self reported educational attainment.

How long is the TMEM160 protein?

The Homo sapiens TMEM160 protein (UniProt Q9NX00) is 188 amino acids long.

Browse: Targets: T · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9NX00
GeneTMEM160
OrganismHomo sapiens
Length188
Binders0
Diseases64
View on UniProt