Thioredoxin-like protein 4B (TXNL4B)
Homo sapiens — UniProt Q9NX01
Data last refreshed: (UniProt release unknown)
Key facts
Thioredoxin-like protein 4B (TXNL4B) is a protein from Homo sapiens identified by UniProt accession Q9NX01, 149 residues long. MolForge cross-references it against 0 known binders and 102 disease associations.
- UniProt accession: Q9NX01; gene symbol TXNL4B.
- Organism: Homo sapiens.
- Length: 149 amino acids.
- Top disease associations (Open Targets): low density lipoprotein cholesterol measurement, haptoglobin measurement and total cholesterol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Thioredoxin-like protein 4B |
|---|---|
| UniProt accession | Q9NX01 |
| Gene | TXNL4B |
| Organism | Homo sapiens |
| Length | 149 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (102)
Diseases linked to this target (Open Targets).
- low density lipoprotein cholesterol measurement · score 0.30
- haptoglobin measurement · score 0.30
- total cholesterol measurement · score 0.29
- blood protein measurement · score 0.28
- hemoglobin measurement · score 0.27
- apolipoprotein B measurement · score 0.26
- erythrocyte count · score 0.26
- serum alanine aminotransferase measurement · score 0.26
- aspartate aminotransferase measurement · score 0.25
- anhaptoglobinemia · score 0.24
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NX01-F1 | alphafold | PREDICTED | 92.55 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NX01.
Amino-acid sequence (149 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TXNL4B?
The strongest Open Targets associations for TXNL4B are low density lipoprotein cholesterol measurement, haptoglobin measurement, total cholesterol measurement, blood protein measurement and hemoglobin measurement.
How long is the TXNL4B protein?
The Homo sapiens TXNL4B protein (UniProt Q9NX01) is 149 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NX01 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NX01 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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