Large ribosomal subunit protein uL16m (MRPL16)
Homo sapiens — UniProt Q9NX20
Data last refreshed: (UniProt release unknown)
Key facts
Large ribosomal subunit protein uL16m (MRPL16) is a protein from Homo sapiens identified by UniProt accession Q9NX20, 251 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q9NX20; gene symbol MRPL16.
- Organism: Homo sapiens.
- Length: 251 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, Alzheimer disease and Parkinson disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Large ribosomal subunit protein uL16m |
|---|---|
| UniProt accession | Q9NX20 |
| Gene | MRPL16 |
| Organism | Homo sapiens |
| Length | 251 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.52
- Alzheimer disease · score 0.29
- Parkinson disease · score 0.29
- lysosomal storage disease · score 0.29
- multiple sclerosis · score 0.29
- sex hormone-binding globulin measurement · score 0.03
- body height · score 0.02
- IGF-1 measurement · score 0.02
- non-alcoholic fatty liver disease · score 0.02
- age-related macular degeneration · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NX20-F1 | alphafold | PREDICTED | 88.76 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NX20.
Amino-acid sequence (251 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MRPL16?
The strongest Open Targets associations for MRPL16 are neurodegenerative disease, Alzheimer disease, Parkinson disease, lysosomal storage disease and multiple sclerosis.
How long is the MRPL16 protein?
The Homo sapiens MRPL16 protein (UniProt Q9NX20) is 251 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NX20 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NX20 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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