Oxidative stress-responsive serine-rich protein 1 (OSER1)
Homo sapiens — UniProt Q9NX31
Data last refreshed: (UniProt release unknown)
Key facts
Oxidative stress-responsive serine-rich protein 1 (OSER1) is a protein from Homo sapiens identified by UniProt accession Q9NX31, 292 residues long. MolForge cross-references it against 0 known binders and 66 disease associations.
- UniProt accession: Q9NX31; gene symbol OSER1.
- Organism: Homo sapiens.
- Length: 292 amino acids.
- Top disease associations (Open Targets): monocyte count, mean corpuscular volume and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Oxidative stress-responsive serine-rich protein 1 |
|---|---|
| UniProt accession | Q9NX31 |
| Gene | OSER1 |
| Organism | Homo sapiens |
| Length | 292 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (66)
Diseases linked to this target (Open Targets).
- monocyte count · score 0.43
- mean corpuscular volume · score 0.39
- platelet count · score 0.37
- lymphocyte percentage of leukocytes · score 0.35
- neutrophil percentage of leukocytes · score 0.35
- monocyte percentage of leukocytes · score 0.34
- systolic blood pressure · score 0.33
- mean corpuscular hemoglobin · score 0.31
- platelet component distribution width · score 0.29
- mean corpuscular hemoglobin concentration · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NX31-F1 | alphafold | PREDICTED | 57.86 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NX31.
Amino-acid sequence (292 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with OSER1?
The strongest Open Targets associations for OSER1 are monocyte count, mean corpuscular volume, platelet count, lymphocyte percentage of leukocytes and neutrophil percentage of leukocytes.
How long is the OSER1 protein?
The Homo sapiens OSER1 protein (UniProt Q9NX31) is 292 amino acids long.
Browse: Targets: O · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NX31 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NX31 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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