DnaJ homolog subfamily C member 28 (DNAJC28)
Homo sapiens — UniProt Q9NX36
Data last refreshed: (UniProt release unknown)
Key facts
DnaJ homolog subfamily C member 28 (DNAJC28) is a protein from Homo sapiens identified by UniProt accession Q9NX36, 388 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.
- UniProt accession: Q9NX36; gene symbol DNAJC28.
- Organism: Homo sapiens.
- Length: 388 amino acids.
- Top disease associations (Open Targets): attention deficit hyperactivity disorder, attention deficit-hyperactivity disorder 8 and schizophrenia 15.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | DnaJ homolog subfamily C member 28 |
|---|---|
| UniProt accession | Q9NX36 |
| Gene | DNAJC28 |
| Organism | Homo sapiens |
| Length | 388 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (31)
Diseases linked to this target (Open Targets).
- attention deficit hyperactivity disorder · score 0.09
- attention deficit-hyperactivity disorder 8 · score 0.07
- schizophrenia 15 · score 0.07
- neurofibrillary tangles measurement · score 0.07
- Asperger syndrome · score 0.06
- Phelan-McDermid syndrome · score 0.06
- self reported educational attainment · score 0.06
- Tourette syndrome · score 0.06
- X-linked non-syndromic intellectual disability · score 0.06
- autism · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NX36-F1 | alphafold | PREDICTED | 75.07 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NX36.
Amino-acid sequence (388 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DNAJC28?
The strongest Open Targets associations for DNAJC28 are attention deficit hyperactivity disorder, attention deficit-hyperactivity disorder 8, schizophrenia 15, neurofibrillary tangles measurement and Asperger syndrome.
How long is the DNAJC28 protein?
The Homo sapiens DNAJC28 protein (UniProt Q9NX36) is 388 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NX36 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NX36 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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