Transmembrane protein 161A (TMEM161A)
Homo sapiens — UniProt Q9NX61
Data last refreshed: (UniProt release unknown)
Key facts
Transmembrane protein 161A (TMEM161A) is a protein from Homo sapiens identified by UniProt accession Q9NX61, 479 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: Q9NX61; gene symbol TMEM161A.
- Organism: Homo sapiens.
- Length: 479 amino acids.
- Top disease associations (Open Targets): diastolic blood pressure, DNA methylation and mean arterial pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Transmembrane protein 161A |
|---|---|
| UniProt accession | Q9NX61 |
| Gene | TMEM161A |
| Organism | Homo sapiens |
| Length | 479 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- diastolic blood pressure · score 0.06
- DNA methylation · score 0.05
- mean arterial pressure · score 0.03
- neoplasm · score 0.02
- non-small cell lung carcinoma · score 0.02
- squamous cell carcinoma · score 0.01
- Crohn's disease · score 0.01
- cancer · score 0.00
- adenocarcinoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NX61-F1 | alphafold | PREDICTED | 85.07 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NX61.
Amino-acid sequence (479 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TMEM161A?
The strongest Open Targets associations for TMEM161A are diastolic blood pressure, DNA methylation, mean arterial pressure, neoplasm and non-small cell lung carcinoma.
How long is the TMEM161A protein?
The Homo sapiens TMEM161A protein (UniProt Q9NX61) is 479 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NX61 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NX61 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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