Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2)
Homo sapiens — UniProt Q9NX62
Data last refreshed: (UniProt release unknown)
Key facts
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase (BPNT2) is a protein from Homo sapiens identified by UniProt accession Q9NX62, 359 residues long. MolForge cross-references it against 0 known binders and 214 disease associations.
- UniProt accession: Q9NX62; gene symbol BPNT2.
- Organism: Homo sapiens.
- Length: 359 amino acids.
- Top disease associations (Open Targets): chondrodysplasia with joint dislocations, gPAPP type, body height and age at menarche.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase |
|---|---|
| UniProt accession | Q9NX62 |
| Gene | BPNT2 |
| Organism | Homo sapiens |
| Length | 359 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (214)
Diseases linked to this target (Open Targets).
- chondrodysplasia with joint dislocations, gPAPP type · score 0.74
- body height · score 0.27
- age at menarche · score 0.23
- brain measurement · score 0.20
- appendicular lean mass · score 0.19
- chondrodysplasia · score 0.19
- neurofibrillary tangles measurement · score 0.17
- allergic disease · score 0.16
- asthma · score 0.16
- adolescent idiopathic scoliosis · score 0.16
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NX62-F1 | alphafold | PREDICTED | 87.72 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NX62.
Amino-acid sequence (359 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with BPNT2?
The strongest Open Targets associations for BPNT2 are chondrodysplasia with joint dislocations, gPAPP type, body height, age at menarche, brain measurement and appendicular lean mass.
How long is the BPNT2 protein?
The Homo sapiens BPNT2 protein (UniProt Q9NX62) is 359 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NX62 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NX62 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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