MICOS complex subunit MIC19 (CHCHD3)
Homo sapiens — UniProt Q9NX63
Data last refreshed: (UniProt release unknown)
Key facts
MICOS complex subunit MIC19 (CHCHD3) is a protein from Homo sapiens identified by UniProt accession Q9NX63, 227 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.
- UniProt accession: Q9NX63; gene symbol CHCHD3.
- Organism: Homo sapiens.
- Length: 227 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, body height and mathematical ability.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | MICOS complex subunit MIC19 |
|---|---|
| UniProt accession | Q9NX63 |
| Gene | CHCHD3 |
| Organism | Homo sapiens |
| Length | 227 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (39)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- body height · score 0.34
- mathematical ability · score 0.32
- self reported educational attainment · score 0.31
- smoking status measurement · score 0.31
- sleep duration · score 0.30
- IGF-1 measurement · score 0.26
- cognitive function measurement · score 0.26
- anxiety · score 0.25
- smoking initiation · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NX63-F1 | alphafold | PREDICTED | 84.69 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NX63.
Amino-acid sequence (227 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CHCHD3?
The strongest Open Targets associations for CHCHD3 are neurodegenerative disease, body height, mathematical ability, self reported educational attainment and smoking status measurement.
How long is the CHCHD3 protein?
The Homo sapiens CHCHD3 protein (UniProt Q9NX63) is 227 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NX63 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NX63 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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