Mediator of RNA polymerase II transcription subunit 29 (MED29)
Homo sapiens — UniProt Q9NX70
Data last refreshed: (UniProt release unknown)
Key facts
Mediator of RNA polymerase II transcription subunit 29 (MED29) is a protein from Homo sapiens identified by UniProt accession Q9NX70, 200 residues long. MolForge cross-references it against 0 known binders and 4 disease associations.
- UniProt accession: Q9NX70; gene symbol MED29.
- Organism: Homo sapiens.
- Length: 200 amino acids.
- Top disease associations (Open Targets): non-small cell lung carcinoma, glioblastoma multiforme and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mediator of RNA polymerase II transcription subunit 29 |
|---|---|
| UniProt accession | Q9NX70 |
| Gene | MED29 |
| Organism | Homo sapiens |
| Length | 200 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (4)
Diseases linked to this target (Open Targets).
- non-small cell lung carcinoma · score 0.05
- glioblastoma multiforme · score 0.04
- neoplasm · score 0.02
- cancer · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NX70-F1 | alphafold | PREDICTED | 72.30 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NX70.
Amino-acid sequence (200 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MED29?
The strongest Open Targets associations for MED29 are non-small cell lung carcinoma, glioblastoma multiforme, neoplasm and cancer.
How long is the MED29 protein?
The Homo sapiens MED29 protein (UniProt Q9NX70) is 200 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NX70 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NX70 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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