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WW domain binding protein 1-like (WBP1L)

Homo sapiens — UniProt Q9NX94

Gene: WBP1LHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

WW domain binding protein 1-like (WBP1L) is a protein from Homo sapiens identified by UniProt accession Q9NX94, 342 residues long. MolForge cross-references it against 0 known binders and 142 disease associations.

  • UniProt accession: Q9NX94; gene symbol WBP1L.
  • Organism: Homo sapiens.
  • Length: 342 amino acids.
  • Top disease associations (Open Targets): monocyte count, glomerular filtration rate and creatinine measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameWW domain binding protein 1-like
UniProt accessionQ9NX94
GeneWBP1L
OrganismHomo sapiens
Length342 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (142)

Diseases linked to this target (Open Targets).

  • monocyte count · score 0.38
  • glomerular filtration rate · score 0.37
  • creatinine measurement · score 0.35
  • type 2 diabetes mellitus · score 0.30
  • lymphocyte:monocyte ratio · score 0.27
  • mean arterial pressure · score 0.25
  • hemoglobin measurement · score 0.24
  • systolic blood pressure · score 0.24
  • diastolic blood pressure · score 0.23
  • body height · score 0.23

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9NX94-F1alphafoldPREDICTED55.33—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NX94.

Amino-acid sequence (342 residues)

MPFLLGLRQD KEACVGTNNQ SYICDTGHCC GQSQCCNYYY ELWWFWLVWT IIIILSCCCV CHHRRAKHRL QAQQRQHEIN LIAYREAHNY SALPFYFRFL PNYLLPPYEE VVNRPPTPPP PYSAFQLQQQ QLLPPQCGPA GGSPPGIDPT RGSQGAQSSP LSEPSRSSTR PPSIADPDPS DLPVDRAATK APGMEPSGSV AGLGELDPGA FLDKDAECRE ELLKDDSSEH GAPDSKEKTP GRHRRFTGDS GIEVCVCNRG HHDDDLKEFN TLIDDALDGP LDFCDSCHVR PPGDEEEGLC QSSEEQAREP GHPHLPRPPA CLLLNTINEQ DSPNSQSSSS PS

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with WBP1L?

The strongest Open Targets associations for WBP1L are monocyte count, glomerular filtration rate, creatinine measurement, type 2 diabetes mellitus and lymphocyte:monocyte ratio.

How long is the WBP1L protein?

The Homo sapiens WBP1L protein (UniProt Q9NX94) is 342 amino acids long.

Browse: Targets: W · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ9NX94
GeneWBP1L
OrganismHomo sapiens
Length342
Binders0
Diseases142
View on UniProt