Syntabulin (SYBU)
Homo sapiens — UniProt Q9NX95
Data last refreshed: (UniProt release unknown)
Key facts
Syntabulin (SYBU) is a protein from Homo sapiens identified by UniProt accession Q9NX95, 663 residues long. MolForge cross-references it against 0 known binders and 75 disease associations.
- UniProt accession: Q9NX95; gene symbol SYBU.
- Organism: Homo sapiens.
- Length: 663 amino acids.
- Top disease associations (Open Targets): cortical thickness, cortical surface area measurement and brain measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Syntabulin |
|---|---|
| UniProt accession | Q9NX95 |
| Gene | SYBU |
| Organism | Homo sapiens |
| Length | 663 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (75)
Diseases linked to this target (Open Targets).
- cortical thickness · score 0.36
- cortical surface area measurement · score 0.36
- brain measurement · score 0.29
- ankle brachial index · score 0.27
- platelet crit · score 0.21
- epilepsy · score 0.07
- Testicular regression syndrome · score 0.05
- female infertility · score 0.05
- 46,XX ovotesticular disorder of sex development · score 0.04
- 46,XX gonadal dysgenesis · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NX95-F1 | alphafold | PREDICTED | 55.34 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NX95.
Amino-acid sequence (663 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SYBU?
The strongest Open Targets associations for SYBU are cortical thickness, cortical surface area measurement, brain measurement, ankle brachial index and platelet crit.
How long is the SYBU protein?
The Homo sapiens SYBU protein (UniProt Q9NX95) is 663 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NX95 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NX95 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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