Very long chain fatty acid elongase 2 (ELOVL2)
Homo sapiens — UniProt Q9NXB9
Data last refreshed: (UniProt release unknown)
Key facts
Very long chain fatty acid elongase 2 (ELOVL2) is a protein from Homo sapiens identified by UniProt accession Q9NXB9, 296 residues long. MolForge cross-references it against 0 known binders and 167 disease associations.
- UniProt accession: Q9NXB9; gene symbol ELOVL2.
- Organism: Homo sapiens.
- Length: 296 amino acids.
- Top disease associations (Open Targets): phosphatidylcholine measurement, phosphatidylethanolamine measurement and phosphatidylinositol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Very long chain fatty acid elongase 2 |
|---|---|
| UniProt accession | Q9NXB9 |
| Gene | ELOVL2 |
| Organism | Homo sapiens |
| Length | 296 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (167)
Diseases linked to this target (Open Targets).
- phosphatidylcholine measurement · score 0.46
- phosphatidylethanolamine measurement · score 0.42
- phosphatidylinositol measurement · score 0.41
- blood metabolite measurement · score 0.40
- docosahexaenoic acid measurement · score 0.37
- docosapentaenoic acid measurement · score 0.36
- glycerophospholipid measurement · score 0.36
- diacylglycerol 38:5 measurement · score 0.31
- cholesteryl ester 22:6 measurement · score 0.31
- fatty acid measurement · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q9NXB9-F1 | alphafold | PREDICTED | 86.69 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q9NXB9.
Amino-acid sequence (296 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ELOVL2?
The strongest Open Targets associations for ELOVL2 are phosphatidylcholine measurement, phosphatidylethanolamine measurement, phosphatidylinositol measurement, blood metabolite measurement and docosahexaenoic acid measurement.
How long is the ELOVL2 protein?
The Homo sapiens ELOVL2 protein (UniProt Q9NXB9) is 296 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q9NXB9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q9NXB9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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